FiberCyte

Build complex 3D cultures, without the equipment.

With FiberCyte you can build perfusable channel networks inside hydrogels. Vascularized tissue models and complex 3D cultures.

Channels
Micrometer-scale, high-resolution features
Hydrogels
5+ matrices supported, not locked to one gel
Format
Standard organ-on-chip devices, chamber slides or well plates

Why FiberCyte

Simple where bioprinting is not.

Real tissue is vascularized. Most models are not, because building them is slow, expensive and needs specialist equipment. FiberCyte is plug and play.

BioprintingFiberCyte
EquipmentA costly printer and someone trained to run itNone. It works in the chips you already run
Living cellsStruggles once cells are involved, extensive optimizationCells grow on the template or in the gel. No post-seeding, no pre-treatment
ResolutionLimitedMicrometer-scale, high-resolution features
WorkflowSlow to set up for each new modelThree steps, minutes to remove the template

How it works

The template disappears. The channel remains.

Three steps, from template to perfusable channel.

TemplateA bare sacrificial template
Or, with cells already grown on itThe same template with cells already grown on its surface
1

Place the template

A sacrificial template is placed in the chip. Cells can be grown on its surface beforehand, or seeded later.

Hydrogel containing cells, cast around the template
2

Embed in hydrogel

Hydrogel containing your cells is cast around the template and crosslinked, locking the geometry in place.

The template is gone, leaving a cell-lined, perfusable channel in the gel
3

Remove the template

The template is removed under mild conditions in minutes. What remains is a clean, cell-lined, perfusable channel.

No toxic solvents.No cell damage.No new equipment.

Demonstrated

What has been built with it

Fluorescence micrograph of nerve fibres growing along and out from a channel
Nerve outgrowth along a templated channel.

  1. Blood-brain barrier

    Endothelial cells and astrocytes in physiologically correct geometry.

  2. Perfused microvasculature

    Endothelial-lined channels with supporting stromal cells.

  3. Nerve outgrowth

    Schwann-cell conduits guiding human axon growth across channels.

  4. Innervated organoids

    Endometriosis organoids reached and innervated through the channels.

  5. Branched networks

    Multi-branch architectures, not just single straight channels.

  6. Automated handling

    Proof-of-concept on an industrial partner's robotic system.

Contact

Working with early partners

We're accepting pilot collaborations with pharma, biotech, academic and organ-on-chip teams.

info@fibercyte.com

Not ready for a pilot? We're also running short conversations with people building 3D models today: 20 minutes, no pitch. Happy to talk.